With two years field randomized block experiment,this study researched the changes of yield of maize and soil enzymatic activity and nutrient content in 0～30 cm under different nitrogen management modes.The field experiments including eight fertilization treatments:No N fertilizer application(CK),once applying common urea as base fertilizer(PU1),conventional applying common urea(PU2),layered applying common urea(PU3,top layer∶middle layer∶bottom layer=2∶3∶5),slowreleased(PCU)and common urea(PU)mixed layered applying,including PCU1(PCU∶PU=middle 3∶7,bottom 3∶7),PCU2(PCU∶PU=middle 5∶5,bottom 5∶5),PCU3(PCU∶PU=middle 3∶7,bottom 5∶5),PCU4(PCU∶PU=middle 5∶5,bottom 3∶7).The results showed that PU2 had higher content of soil nutrient and enzymatic activity in top 0~10 cm soil.There was no significant difference among other treatments except CK.Compared with the treatments of common nitrogen(PU1,PU2,PU3)，The content of organic matter,total nitrogen,available nitrogen of the treatments of release urea combined with common urea(PCU1,PCU2,PCU3,PCU4)in the soil of 10～20 cm were increased by 0.48%～5.66%,2.61%～7.64%,11.57%～43.30%,the treatment of PCU4 had the highest content which were 24.30 g/kg,1.61 g/kg,84.28 mg/kg.The content in 20～30 cm soil were increased by 0.68%～7.32%,3.37%～9.04%,2.51%～26.17%,the treatment of PCU2 had the highest content of which were 24.13 g/kg,1.33 g/kg,72.23 mg/kg.The content of urease,catalase,sucrase,alkaline phosphatase in the soil of 10～20 cm were increased by 2.49%～8.33%,7.25%～28.12%,1.05%～13.79%,14.57%～73.16%,the treatment of PCU4 had the highest content which were 0.60 mg/g,1.04 mol/L,29.15 mg/g,0.98 mg/g,the contents in 20～30 cm soil were increased by 9.52%～15.91%,9.60%～32.14%,12.26%～36.69%,26.40%～45.42%,the treatment of PCU2 had the highest content which were 0.60 mg/g,1.07 mol/L,25.27 mg/g,0.87 mg/g.Compared with PU3,the treatment of release urea combined with common urea applied increased the yield of maize by 1.78%～15.85% and 2.32%～24.56% in the two years,and the PCU4 had the highest yield with 13 016 kg/hm2 and 13 899 kg/hm2.Slowreleased and common urea mixed layered applying can increase the content of nutrient and enzymatic activity of 10～30 cm soil,and increase the yield of maize,the treatment of PCU4 is the best cultivation and fertilizer application method.