field plot experiment was carried to study the effect of different proportion of organic nitrogen and inorganic nitrogen on the improvement of soil secondary salinization and the effect on yield and quality of tomato.The results showed that the organic nitrogen and inorganic nitrogen fertilizer could obviously reduce the total salt content and the EC in the soil，significantly reduces the excessive accumulation of nitrate nitrogen in soil，especially with the organic nitrogen and inorganic nitrogen ratio of 2∶1，which has the best effect.Meanwhile，organic nitrogen and inorganic nitrogen were applied to improve the balance and regulation of soil organic matter.The organic matter increased from 16.8 g/kg to 21.7 g/kg.Organic nitrogen and inorganic nitrogen 2∶1 could significantly reduce the nitrate content in tomato，significantly increase soluble total sugar and ascorbic Vc content in tomato，increase yield and improve fruit quality of tomato.From the two aspects of soil secondary salinization and high quality fertilization management,organic nitrogen and inorganic nitrogen combined application was suggested in the greenhouse，when soil total salt content was 3.54 g/kg，the ratio of organic nitrogen and inorganic nitrogen 2∶1 was optimal.