Taking four-year“Cabernet Sauvignon”grape as the researchobject，two -year continuous applications of EDTA-Zn fertilizer with drip irrigation at five level[0 kg/hm²(CK)，24.5 kg/hm²(T1)，34.0 kg/hm²(T2)，43.5 kg/hm²(T3)， 53.0 kg/hm²(T4)，62.5 kg/hm²(T5)]，and combined with foliar spraying at fivelevel[0 kg/hm²(CK)，0.5 kg/hm²(T1)， 1.0 kg/hm²(T2)，1.5 kg/hm²(T3)，2.0 kg/hm²(T4)，2.5 kg/hm²(T5)]in field trials were conducted to investigate the effectof supplementing zinc fertilizer on zinccontent，growth and quality of wine grapes at strong alkaline limestone soil(pH>8.5).The results showed that zinccontent，grainsize，earlength，100-grain weight and yield of wine grapes increased by 42.1%～78.7%，2.6%～28.2%，10.1%～22.3%，3.0%～ 8.8% and 17.2%～216.6%，compared with no zincfertilizer(CK).At the same time，compared with no zinc(CK)，the tannin content of wine grapes decreased by 42.0%～67.9%，andthe anthocyanins，totalphenols，soluble solids and soluble sugar content increased by 0.7%～71.9%，5.0%～80.6%，9.3%～ 24.0% and 10.4%～29.4%，while the titratable acid content did not increase significantly except T 4.Correlationanalysis showed that zinc content was significantly correlated with ear length，100-grainweight，particlesize，yield，totalphenol and solublesugar.The analysis of zinc content and quality of synthetic wine grapes showed that T 3 treatment was thebest.Under the condition of calcareous soil in Helanmountain，Ningxia，the application rate of about 45 kg/hm² EDTA-Znis suitable for improving the zinccontent，yield and quality of wine grapes.