The effects of substrate with inoculation of mycorrhiza on soil salinity and nutrients of processingtomato( “Tunhe 5501”)at seedlingstage，floweringstage，fruit settingstage，fruit enlargement stage and harvest stage were studied by potexperiment.The results showed that the salt content of mycorrhizal seedling treatment was lower than that of non -mycorrhizalseedlingtreatment，and there were significant differences in mild salinized and moderate salinized soil from flowering to fruitsettingstage，and decreased by7.2%，9.9% and11.3%，22.5%，respectively，while the soil pH increased graduallywith the growthperiod.The contents of organic matter，available Ncontent，available phosphorus content and availablepotassium content were all characterized by severely salinized soil>moderately salinized soil>mildly salinized soil，andincreased by14.4%，102.2%，40.4% and 43.1% in severely salinized soil than mild salinizedsoil，respectively.The nutrient contents of non-myeorrhizal seedling treatment were higher than mycorrhizal seeding treatment，and decreasedwith the growthperiod.The yield of processing tomato decreased with the increase of soil salinization degrees.However， the yield of myeorrhizal seedling was higher than non-mycorrhizal seedling in the mildly salinized，moderate salinized andseverely salinizedsoil，increased by11.8%，14.5% and 13.2% respectively.It indicated that substrate with inoculation ofmycorrhiza could reduce the accumulation of salt in different salinesoil，promote the transformation of soil mineralnutrients，relieve the persecution of crops caused by saltstress，promote the absorption of mineral nutrients by mycorrhizal under saltstress，and promote the plantgrowth，enhance plant tolerance to saltstress，and ultimately increaseyield.