The effects of different vermicompost extracts on the growth of tobacco seedlings were explored to provide a theoretical basis for the application of vermicompost extract.Firstly，using pig manure vermicompost and food waste vermicompost as raw materials，the different vermicompost extracts were obtained.The experiments of tobacco seedling cultivation with different concentrations of vermicompost extracts were carried out using the improved Hoagland nutrient solution as the control (CK).The results showed that adding vermicompost extract promoted the growth and development of tobacco seedlings in varying degrees.With the increase of the proportion of vermicompost extract，it showed a trend of first increasing and then decreasing.The comprehensive effect of vermicompost extract with 7.5% mass concentration was the best，and the overall seedling raising effect of 7.5% mass concentration of the food waste vermicompost extract was better than the pig manure vermicompost extract.Compared with the CK，the plant height，stem diameter and SPAD value of food waste vermicompost extract with 7.5% mass concentration were increased by 118.06%，207.05%，19.28%，G value，strong seedling coefficient，root activity increased by 450.00%，600.00%，150.00%，and total root length，root surface area，root volume，root tip number increased by 272.23%，449.25%，700.00%，613.51%，respectively.It is suitable to be used as high-quality raw material of vermicompost extract.In conclusion，7.5% mass concentration of the vermicompost extract is suitable for tobacco seedling cultivation，and the food waste vermicompost extract has the best effect.