The recent research on the mechanisms of Zn accumulation and the relevant approaches to increasing Zn density in grain of food crops was overviewed and discussed.Actually Zn uptake,transport and accumulation in edible portions of seeds were controlled by complex soil and plant factors: 1) Zn uptake from soil; 2) Zn transport and accumulation in nongrain;3) Zn accumulation in grain.Increasing the Zn content and bioavailability in grains could be attainable through agricultural practices,including genetic improvements through traditional plant breeding or molecular biological techniques,and other optimal cultivation practices.