In order to increase production and improve the quality of strong gluten wheat that grown in the sand on the ground suitable for planting area,conventional field trials and statistical analysis methods which was combined with quality test were conducted.The results showed that,cultivation of strong gluten wheat in eastern Henan plain sand on the ground,on the base of application of a certain amount of P and K,application of nitrogen 75~375 kg/hm2,increased yield 197%~635%,with an average yield increased 477%;Grain protein content increased 09~25 centesimal point,with an average relativeincrease of 157%300 kg/hm2 nitrogen fertilization the amount of stimulation effect and the improvement of grain quality and flour processing quality traits optimal,the nitrogen application ratio of nitrogen phosphorus and potassium(N∶P2O5∶K2O)was 2∶1∶12.Nitrogen fertilizer total of 300 kg/hm2 test conditions,by means of “base fertilizer and topdressing equilibrium supply”(the percentage of both base fertilizer and topdressing was 50%),“the topdressing twice distribution”(the percentage of topdressing in shooting stage was 30%，in booting stage was 20%),which was“532” fertilization mode,wheat yield and quality factors more coordinated.This method could be used in the eastern Henan sand area current production,ecological and technical conditions for the purpose of high yield and quality of cultivation strong gluten wheat as nitrogen distribution of the main technical measures.