The effects of fertilizer application on production,biomass dry weight and element distribution in various organs of trellis cultivated Melon(Cucumis melo L.)were investigated by field experiments.Five fertilizer treatments were designed,ieno fertilizer(CK),nitrogen phosphorus fertilizer(NP),and nitrogen potassium fertilizer(NK),phosphorus potassium fertilizer(PK),and nitrogen phosphorus potassium fertilizer(NPK).The results showed that N content in various organs of melon was in the order of seed＞leaf＞stem＞root＞flesh;P content was in the order of seed＞leaf＞root＞flesh＞stem;K content was in the order of stem＞leaf＞flesh＞root＞seed.Fertilizer application increased the differences in dry matter weight in various organs,and improved photosynthetic products transportation from other organs to fruit.Fruit yields were increased from 191% to 510% under the different fertilization.Fertilizer application reduced the differences in N,P,Cu,Fe and Zn content in various organs,and increased the differences in K content.The response extent of N,P and K elements to fertilizer application was larger than Cu,Zn,Fe,and Mn elements.The response extent of leaf and stem was larger than fruit portion.The response of elements to NPK fertilizer treatment was bigger than other fertilizer treatments.Besides,element distribution in various organs was also influenced by the mutual effect of fertilizer varieties.Application of nitrogen,phosphorus combined with potassium fertilizer could better change N,P,K,Cu,Zn,Fe,Mn elements distribution in various organs of melon.