Effects of three fertilization patterns using negative pressure irrigation device on tomato growth and yield were studied by greenhouse tomato cultivation.There treatments were set up:CK(negative pressure irrigation with conventionaldressing fertilization),T1(EC adjusted with conventional fertilizer treatment),T2(a large number of elements Yamazaki tomato fertilization treatment). The results showed that there was no significant difference on plant height,leaf number and quality among the three treatments,but stem diameter of T2 was significantly greater than CK and T1.The maximum net photosynthetic rate,weight,yield and fruits quality of T2 were all highest,and increased by 13% and 11% than those of CK and T1.During the growth period,nitrogen use efficiency of T2 was the highest,and increased by 12% and 10% than those of CK and T1.Integrated tomato growth,yield and nitrogen use efficiency,T2 effectively controlled water and fertilizer supply to meet the full nutrients demand for crop,and should be recommended as a new mode of fertigation in greenhouse vegetable production.