A “3414” fertilization experiment was conducted to build the regression model between yield and the amounts of N，P，K applications and obtain the optimized fertilization for summer black seedless grape in southern China.The result showed that nitrogen was the key factor for yield，followed by phosphorus and potassium.Under the condition of the soil，the optimum application of N，P2O5 and K2O were 363.6 kg/hm2，454.95 kg/hm2，363.3 kg/hm2 respectively.Among all the treatments，the highest yield occurred in the treatment 6 with application of nitrogen，phosphorus and potassium of N 300 kg/hm2，P2O5 270 kg/hm2，K2O 375 kg/hm2，which increased by 65.91% than control.The content of TSS/TA，the ratio of output to input of treatment 6 were also higher，which indicated to a better quality in comprehensively.