An analytical method for the simultaneous determination of 3 sulfonylurea herbicides(Chloride methyl,Methyl methyl,Tribenuron )was established by matrix solidphase dispersion extraction(MSPD)with high performance liquid chromatography tandem mass spectrometry(HPLCMS/MS).Based on ball milling of sample pretreatment of MSPD,the extraction conditions were optimized in detail as following:grinded about 0.2 g soil sample and 0.8 g HCC18 solid phase extraction powder with 8 mm small steel ball for 10 min and then loaded into the empty glass extraction column.The mixture was eluted with 10 mL of acetone,and concentrated to 0.6 mL with methanol,then choulved by the 0.22 μm membrane and then transfered to the automatic sample bottle.The 3 sulfonylurea herbicides were separated upon a Syncronis C18 column using methanol（A）~1‰ formic acid solution(B)as mobile phase by gradient elution，and detected by MS under selected reaction monitoring(SRM)mode.The results indicated that the Chlorsulfuron achieved the good linearities in the range of 20~200 μg·kg －1,and the other two sulfonylurea herbicides achieved the good linearities in the range of 10~200 μg·kg －1,with correlation coefficients from 0.997 9~0.999 5.The recoveries at three spiked levels were ranged from 84.7%~104.6% and RSDs were 4.5%~7.9%.The limits of detection(LODs)for the target compounds ranged from 0.32~0.68 μg·kg－1 .The suggested method was simple,efficient,and less interference with high recovery rate,and met the analytical requirements of herbicide residues in soil.