Based on the 8year field experiment，this research analyzed the seasonal variations and effecting factors under different tillage and fertilization treatments.The results indicated that different tillage and fertilization treatments significantly affected the soil respiration rate，compared with conventional tillage，notillage with straw mulching treatment obviously decreased the respiration rate of dry farmland soil.Under the equivalent tillage treatment，the soil respiration rate was distinctly improved when manure increased applied.On account of the above aspects，it showed that both tillage and manure application contributed to the soil respiration.Seasonal soil temperature and moisture of winterwheat were the main factors to influence soil respiration of which soil temperature and soil moisture explained 83.2%～93.7% and 44.0%～76.5% respectively of soil respiration.The effect of soil temperature on soil respiration was fairly greater than that of soil moisture.Meanwhile，the effect degree of the soil temperature on soil respiration varied from different tillage and fertilization treatments.In addition，tillage and manure raised the temperature sensitivity of soil respiration，and notillage with straw mulching reduced the impact of temperature.