Pot experiments were conducted to study the effects of soil application of cadmium-hyperaccumulator plant straw(Solanum nigrum，Crassocephalum crepidioides，Bidens pilosa)on grape growth and cadmium content under cadmiumstress. The results showed that the biomass，photosynthesis intensity，antioxidant enzyme activity and metabolite content in grape seedlings increased after applying S. nigrum，C. crepidioides and B. pilosastraw，while the cadmium content inshoots of grape seedlings decreased by37.63%，18.31% and22.25%，respectively，compared with that without application. The tree experiment showed that the cadmium content in grape fruits decreased and the quality of grape fruits improved after applying S. nigrum，C. crepidioides and B. pilosastraw. The cadmium content in grape fruits decreased by22.11%，14.07%and19.25%，respectively，compared with that without application.Therefore，soil application of S. nigrum，C. crepidioides and B. pilosastraw can promote the growth of grapes and reduce their cadmiumcontent，which is conducive to the normal growth and safe production of grapes in cadmium-contaminatedorchards，and amongthem，applying S. nigrum straw had the best effect.