The poor improvement of soil acidity is one of the main problems that lead to high mortality of blueberry.The waste water of diosgenin extraction industry was used as the main raw material of soil improvement，and the liquid method of soil acidity improvement was established.Then it was compared with the traditional method of sulfur powder improvement for blueberry planting.The results showed that the accuracy and stability of soil pH regulation was the key factor affecting the survival of blueberry seedlings.At the end of 127 d，the soil pH of the diluted wastewater，dilute sulfuric acid and 10 g sulfur powder treatments was maintained accurately and stably at about 5.5，and the survival rate of blueberry seedlings in the three groups were 100%，while that in the 5，30，50，100 g sulfur powder group were 0%.The results of growth index analysis showed that when the soil pH was suitable，the seedling growth of sulfur powder group was better than that of dilute wastewater and dilute sulfuric acid groups.The indicators of biomass，root volume，root length，plant height，leaf number，branch number of the 10 g sulfur powder improvement group were about twice as high as those of the dilute wastewater improvement group and the dilute sulfuric acid control group.There was little effect on nitrogen metabolism，phosphorus metabolism and organic matter catabolism by the three groups.In short，the results showed that soil pH was the key factor affecting the survival of blueberry seedling，and sulfur powder should have nutrition effect on blueberry.