Zinc is one of the most important essential trace element for crops，and its application plays a crucial role in the growth and development of crops. However，when zinc fertilizer is applied to soil，its availability will decrease，leading to a low use efficiency. Therefore，improving the availability of zinc fertilizer has been widely concerned. Nitrogen is the most necessary element and in great demand for crops，and has a synergistic effect with zinc. Rational combined application of nitrogen and zinc can not only enhance zinc availability，but also improve the utilization rate of nitrogen fertilizer. At the same time，this combined application also has a certain positive effect on crop growth and nutrient absorption，and increases crop yield. However，the synergistic effect of nitrogen and zinc varies with soil type and crop type. Therefore，it is of great significance to review the efficiency and its influencing factors of combined application of nitrogen and zinc on different soil types and different crops. Through analying a large number of literatures，and reviewed the research works on the combined application of nitrogen and zinc on different soil types and different crops，and analyzed the influencing factors of nitrogen-zinc fertilizer application effect，and found that: Nitrogen application can promote the absorption and transport of zinc in crops，and thus increase the concentration of zinc in crop grains. Zinc application can also improve the uptake and utilization of nitrogen by promoting nitrogen metabolism. The combined application of nitrogen and zinc has obvious synergistic effects: (1)Promote the growth，yield and quality of crops；(2)Increase the absorption of nitrogen and zinc. However，these synergistic effects vary with the different crop types，soil properties，application ratio of nitrogen and zinc and application mode. Scientific application of nitrogen and zinc is beneficial to high yield and high quality of crops，but there are few studies on the mechanism of nitrogen and zinc application at present，and the technology of nitrogen and zinc application also needs to be further optimized. Therefore，it is necessary to strengthen the research on the interaction mechanism of nitrogen and zinc，and clarify the appropriate ratio and method of nitrogen and zinc application under different conditions. This will provide technical basis and theoretical guidance for promoting efficient utilization of zinc and developing new nitrogen-zinc fertilizer products.