To investigate the relationship between the soil physicochemical properties and the main chemical compositions of tobacco leaves，the samples of soil and tobacco leaves were collected and analyzed from 12 tobacco-planting areas in Dali.The results showed that，①The soil texture was mainly heavy loam in Dali tobacco-planting areas，the pH value and the content of available potassium were generally suitable，the contents of organic matter，available nitrogen，available phosphorus，water soluble chlorine and available boron were generally higher，and the content of available potassium in Dali city was lower and the content of water soluble chlorine in Yangbi county was on the high side among them.②In general，the content of total sugar and the ratio of sugar and nicotine of tobacco leaves were too high，and the other items contents were medium in Dali.However，the chlorine content was relatively high and the total nitrogen content and the potassium to chlorine ratio were relatively low in Midu county，the starch content in Dali city were slightly higher，and the nitrogen to nicotine ratio were in a low level in Weishan，Nanjian，Jianchuan，Yangbi，Eyuan and Midu county. ③The common results by applying simple and canonical correlation analysis displayed that there was an extremely significantly negative correlation between the potassium content in tobacco leaves and the pH value in soil，a very significantly positive correlation between the total nitrogen and nicotine content in tobacco leaves and the contents of organic matter，available nitrogen and available boron in soil，and a quite significantly negative correlation between starch content in tobacco leaves and the contents of organic matter and available nitrogen in soil with a certain range.