Using 5-year-old ‘Kyoho’ grape as the test material，and applying organic fertilizers according to different proportions of chemical fertilizer reduction the effects of different chemical fertilizer reduction combined with organic fertilizer on the grape yield，quality and soil quality were studied with two consecutive years of field experiment in order to obtain the best ratio of chemical fertilizer reduction combined with organic fertilizer.The results showed that compared with the application of chemical fertilizer(CK)，the reduction of chemical fertilizer combined with organic fertilizer improved grape yield and quality，but also effectively reduced the accumulation of large amounts of elements in the soil，increased soil organic matter content，improved soil structure and alleviate soil acidification.The T2 treatment was the best treatment，organic fertilizer 15000 kg/hm²+compound fertilizer 675 kg/hm²+potassium sulfate 330 kg/hm².In the second year，compared with CK treatment，the single fruit weight，single ear weight and yield of T2 treatment increased significantly by 15.90%，25.41% and 33.68%，respectively.The soluble solid content，pH value，Vitami C content and solid acid ratio of T2 treatment increased by 6.41%，2.16%，25.17% and 19.98%，respectively，and the titratable acid content decreased by 11.32%.Based on the results，the reasonable reduction of chemical fertilizer combined with organic fertilizer could improve the soil quality and improve the yield and quality of grape.