In order to study the regulation effect of foliar spraying with growth regulator on seed yield of Chinese milk vetch，using “Xinzi1” as test material，foliar spraying with paclobutrazol(PP333)，6-benzylaminopurine(6-BA)，brassinolide(BR)，alginate oligosaccharides(AOS)and compound(NCD)was performed at the squaring stage，while spraying clear water was used as the control.The results showed that compared with the control of spraying clear water，treatment with PP333 significantly inhibited the plant height，while treatment with PP333，BR and NCD significantly promoted the increase of stem diameter，branch number，plant weight and SPAD.Analysis of yield composition showed that，the seed number was significantly increased by 29.11%，21.52% and 30.06% when spraying with PP333，6-BA and NCD，respectively，compared with that of the control.However，the seed number of BR and AOS treatments was not significantly different from that of the control.The 1000-seed weight was significantly increased by 30.77%，21.05% and 32.79% when spraying with BR，AOS and NCD，respectively，compared with that of the control.However，the 1000-seed weight of PP333 and 6-BA treatments was not significantly different from that of the control.The pod numbers of all sprayed with growth regulators treatments were significantly higher than that of the control.The seed yields under NCD，PP333，BR，6-BA and AOS treatments were significantly higher than that of the control，with increases of 29.73%，22.02%，19.02%，10.52% and 10.01%，respectively.The seed yield under NCD treatment was the highest，reaching 601.37 kg/hm².In conclusion，foliar spraying with growth regulator at squaring stage could significantly promote the increase of seed yield，and the NCD treatment had the best effect.The seed yield of PP333 and 6-BA treatments increased mainly by increasing pod number and seed number，that of the BR and AOS treatments increased mainly by increasing pod number and 1000-seed weight，and NCD increased final seed yield by increasing pod number，seed number and 1000-seed weight.