According to the standard HJ 832-2017，the contents of chromium(Cr)，nickel(Ni)，copper(Cu) and lead(Pb) in the solution was prepared and then determined by ICP-MS in the standard mode.The experiments were divided into three stages.The repeatability test of two soil reference materials were determined at the first stage from June to July in 2019.The accuracy and precision of the two soil reference materials were further verified and analyzed at the second stage from April to May in 2020.The performance of the instrument was adjusted，and the signal values of Mg，In and U were optimized to determine the content of Pb in soil at the third stage from July to August in 2020.The detection limit and recovery rate of ICP-MS(DRC-Ⅱ) for Cr，Ni，Cu and Pb in soil were analyzed.The results showed that the accuracy and precision of ICP-MS(DRC-Ⅱ) for determination of total contents of Ni，Cu，Cr and Pb in soil met the analytical requirements.The detection limits of Ni，Cu，Cr and Pb were 0.060，0.010，0.045 and 0.015 mg·kg-1，respectively，with the recoveries from 89.6% to 112.3%.