It has great significance to clarify the spatial distribution of soil exchangeable magnesium and soil acidification status which can serve as a basis of management，precision fertilization and sustainable development in flue-cured tobacco cultivation of Fujian province.Based on 1199 surface tobacco-planting soil samples collected at 2018 in Fujian province，the spatial distribution of exchangeable magnesium and soil acidification in Fujian province were revealed from different perspectives by using global Moran’s I index，cold and hot spot analysis and Kriging interpolation.The results showed that the average content of exchangeable magnesium in Fujian tobacco-planting soil was 70.10 mg/kg and among them 84.66% of the tobacco-planting soil was magnesium deficient or extremely deficient.The spatial distribution of exchangeable magnesium showed contiguous and patchy.Its value trend was Nanping>Longyan>Sanming and the highest content was 81.06 mg/kg in Nanping.The average pH value was 5.19 in the tobacco-planting soil of Fujian province and about 83.24% of the soils area the pH was at low or very low level(pH<5.5).The phenomenon of acid soil contiguous distribution was obvious.The soil acidification was most prominent in Sanming tobacco-planting soil area with 5.08 pH. The spatial distribution of exchangeable magnesium and pH was aggregated and the spatial auto-correlation was significant.Soil acidification and magnesium deficiency were still prominent in tobacco-cultivated areas of Fujian province.