Methods for analysis of 19 elements in pressed and fusion soil samples，including As，Co，Cr，Cu，Mn，Ni，P，Pb，S，Ti，V，Zn，Al2O3，Cao，Fe2O3，K2O，MgO，Na2O and SiO₂，were established by using wavelength dispersive X-ray fluorescence spectrometer. The effects of sample size and sample preparation method on the determination of 19 elements were discussed. The results of method precision showed that when the contents of As and Co in the samples were more than 10 mg/kg，the RSD values of 19 elements in 0.149 mm(100 mesh)pressed，0.075 mm(200 mesh)pressed and fusion samples were less than 10%. When the contents of As and Co were less than 10 mg/kg，the relative standard deviation (RSD) values of 19 elements of 200 mesh pressed were less than 10%. The accuracy results showed that the accuracy of pressed reference material with more than 5 mg/kg As，Co，Cu and all contents of other 16 elements met the requirements；the accuracy of fusion reference materials with high contents of As，Co，Cu，Pb and other 15 elements met the requirements. The experimental results of different particle sizes showed that when the elements contents were more than 10 mg/kg，the RSD values of 19 elements in 100 mesh and 200 mesh pressed results were less than 10%. The experimental results of different sample preparation methods showed that，fusion preparation was not applicable to analysis As，Co，Cu and Pb elements with low content，the RSD values of Cr，P，S，Mn，Ni，V，Zn，Ti，Al2O3，CaO，Fe2O3，K2O，MgO，Na2O and SiO₂ with fusion and pressed preparation were less than 10%. The pressed preparation method has simpler operation and lower cost，it is more suitable for the analysis of 19 elements such as As，Co，Cr，Cu，Pb，P，S，Mn，Ni，V，Zn，Ti，Al2O3，CaO，Fe2O3，K2O，MgO，Na2O and SiO₂ in a large number of soil samples. For samples with As and Co above 10 mg/kg，accurate and reliable results can be obtained by using 100 mesh and 200 mesh pressed samples. For samples with As and Co below 10 mg/kg，it is recommended to use 200 mesh sample pressed preparation.