In order to solve the problems of revegetation degradation and soil fertility decline，granular organic fertilizer and sheep board manure in pastoral areas were selected as experimental materials for improving soil in Muli mining area of Qinghai，and a two-factor random block control experiment was conducted at slope and flat plots to provide theoretical basis for ecological recovery in alpine mining area. A total of sixteen treatments combined with sheep board manure and granular organic fertilizer were set up，including four levels of the ratio of sheep board manure and mine muck，which were 0∶10(0 m3/m2，S0)，1.5∶10(0.03 m3/m2，S1)，3∶10(0.06 m3/m2，S2)，4.5∶10(0.09 m3/m2，S3)，and four levels of granular organic fertilizer application，which were 0 kg/m2(M0)，1.2 kg/m2(M1)，2.4 kg/m2(M2)，3.6 kg/m2(M3). The results showed that:(1)The maximum soil water holding capacity，capillary water holding capacity and capillary porosity of the flat plot under M3S2 treatment were 3.9，4.1 and 1.8 times higher than those under M0S0 treatment，and the soil bulk density reduced by 42.8% compared with that of M0S0 treatment. The maximum soil water holding capacity and capillary porosity of the slope plot under M3S2 were 70.6% and 75.0% higher than those of M0S0 treatment，and the capillary water holding capacity was 2.2 times higher than that of M0S0 treatment.(2)The single application of sheep board manure and its combined application with granular organic fertilizer increased the soil nutrient content and soil pH in the flat plot. The contents of total nitrogen，total phosphorus and organic matter in flat plot under M1S3 treatment were 2.0，1.9 and 1.9 times that of M0S0 treatment，respectively. The content of ammonium nitrogen under M3S2 treatment was 3.1 times that of M0S0 treatment. Soil total nitrogen in the slope plot significantly increased by 64.3% under M1S2 compared with M0S0 treatment.(3)Soil urease activity in the flat and plot land significantly increased under M1S3 and M3S3 treatments.(4)Soil total nitrogen，capillary porosity and ammonium nitrogen were the driving factors affecting soil enzyme activities. On the whole，the treatment effect of granular organic fertilizer combined with sheep board manure M1S3 is the best for the reconstructed soil without guest soil in the flat plot of mining area，and M3S2 is the best for the reconstructed soil without guest soil in the slope plot of mining area.