The effects of different optimal fertilization modes on yield，quality and tree growth of‘Hongmeiren’ orange were studied to provide technical guidance for achieving high yield and quality of‘Hongmeiren’ orange with a field experiment.Four treatments were set up:farmer conventional fertilization(FP)，farmer+trace element optimization(OM)，organic fertilizer with special fertilizer(OPM)，integrated optimization fertilizer(COM).Three optimized fertilization modes promoted the growth of‘Hongmeiren’ orange，the OM treatment significantly increased the vitamin C content，and the OPM treatment had the potential to improve the yield and quality of orange.The COM treatment had the best effect，which significantly increased the growth indexes of spring shoot，compared with FP treatment；The leaf SPAD value and mineral nutrient content were significantly increased；Fruit diameter，fruit number and yield were significantly increased by 6.91%，19.62% and 26.45%，respectively；the vitamin C，soluble solid and solid acid ratio of fruit were significantly increased by 66.91%，22.42% and 35.93%，respectively. Comprehensive optimization of nutrient management can balance tree nutrients，stimulate tree yield potential and improve the fruit quality.