The irrational fertilization phenomenon is common in ginger production in our country. Studying the effects of different organic and inorganic fertilizer dosages and ratios on gingergrowth，nutritionalquality，and yield can provide reference for efficient fertilization and high-quality ginger production. At the sametime，it is also an important measure to improve ginger production efficiency and protect the ecological environment. Under fieldconditions，using Shandong Laiwuginger( Zingiber Officinale Roscoe)asthe testmaterial，organic and inorganic fertilizers were used as experimental factors. A two-factor，three -level complete block design wasadopted，with atotal of 9 treatmentcombinations，includinglow，medium， and high levels of organic and inorganic fertilizers. All organic and inorganic fertilizers were applied as base fertilizers. At the mature stageof ginger，three samples of ginger from each plot were randomly collected to measuregrowth parameters， nutrientabsorption，qualityindicators，and yield. The study found that the combined application of various organic and inorganic fertilizerspromoted ginger growth anddevelopment，increased the absorption of mineral elements such asN，P，K，Fe，Zn，improved gingerquality，and increased gingeryield. Comparatively，treatmentT6(organic fertilizer 45 t·hm-2 + compound fertilizer 2.25 t·hm-2，i.e.，applying organic fertilizer+P2O5+K2O=400.5+1390.5+1165.5 kg·hm-2，and applying compound fertilizer N+P2O5+K2O=337.5+135+450 kg·hm-2)had the best overall effect and was the best fertilizer treatmentcombination. Compared with thecontrol，it increased theN，P，and K contents in the aboveground part and ginger rhizomes by 30.07%and25.57%，31.73%and67.68%，43.33%and62.37%，respectively；and increased the contents ofsolublesugars，solubleproteins，gingerols，and curcumin in ginger rhizomes by32.42%，54.15%，35.10%，and49.25%， respectively. The yield of ginger in each treatment was increased from 15.76% to 66.38%. The experimental results indicate that the combined application of organic and inorganic fertilizers can effectively promote gingergrowth，improve nutrientabsorption，enhance ginger rhizomequality，and increase ginger yield. Considering allfactors，the best agricultural fertilization scheme is organic fertilizer 45 t·hm-2 + compound fertilizer 2.25 t·hm-2，which is worth promoting and applying in related areas.