Inductively couple plasma massspectrometry(ICP-MS)was used to compare the extraction effects of wet digestion for 30min，wet digestion to near-dry and microwave digestion oncadmium，arsenic，mercury，lead and chromiumfrom organic fertilizers，and a method for the determination of multiple heavy metal elements from organic fertilizers for the unified measurement by ICP-MS was established. The results indicated that after the wet digestion to near-dry digestion andmicrowave digestion，the method quantification and standard value deviation of five heavy metals content in standard materialfor multielement composition analysis of organicfertilizer(RMH -F001)from standard value wereless than 6.3% and5.7%，respectively，and the estimated values were in line with the standard value range. The stability of data under the treatment of microwave digestion with nitric acid-hydrogen peroxide system wasthebest，the relative standard deviation was0.8%-6.8%， the relative deviation was1.1%-9.0%，relative difference values was 2.2%-18.0% and the standard addition recoveries was 99.4%-102.9%. The microwave digestion combined with ICP-MS could be used as a conventional method for the unified measurement of five heavy metals in organic manure.