In order to improve the fertilizer utilization rate of rice and reduce the amount of fertilizerapplication，the application effect of organic inorganic compound fertilizer was studied. Six different fertilization treatments were setup， including nofertilization(CK)，conventional fertilization of common compound fertilizer with nitrogen split-application(FFP)，equal nutrient organic inorganic compound fertilizer with one-timefertilization(T1)，equal nutrient organic inorganic compound fertilizer with nitrogen fertilizer split-application(T2)，90% nutrient organic inorganic compound fertilizer with nitrogen fertilizer split-application(T3)，80% nutrient organic inorganic compound fertilizer with nitrogen fertilizer split-application(T4). The effect of organic inorganic compound fertilizer application on rice yield and nitrogen and phosphorus absorption and utilization was studied. The results showed that the contribution rate of dry matter accumulation tograin after anthesis(62.69%-68.48%)was higher than that of dry matter transport tograin(31.52%-37.33%). The actual yield of each treatment ranked as T2>T1>FFP>T3>T4>CK. The yield of T2 and T1 treatments increased by 6.6% and2.2%，respectively，while T3 treatment showed nosignificantdifference，compared with FFP treatments. The uptake and accumulation of aboveground nitrogen and phosphorus in the grain of rice in all treatments accounted for more than 65% and70%，respectively. Compared with FFPtreatment，the uptake and utilization rate of nitrogenand phosphorus fertilizer， the agronomic utilization rate of nitrogen and phosphorus fertilizer and the partial productivity of nitrogen and phosphorus fertilizer in T1 treatment increased by 8.9%and12.9%，0.9%and3.2%，0.9 and 3.2 kg·kg-1，respectively，and those in T2 treatment increased by 1.6%and1.6%，2.6% and9.6%，2.6 and 9.6 kg·kg-1，respectively，while there was no significant difference in T3 and T4 treatment. Combined application of organic inorganic fertilizer can improve the absorption and utilization rate of nitrogen and phosphorus nutrients. In the case of the same total amountof nitrogen，phosphorus andpotassium nutrients， one-time application of organic inorganic compound fertilizer is more conducive to improve the absorption of nitrogen and phosphorus in rice. In the case of split-application ofnitrogen fertilizer，the effect of organic inorganic compound fertilizer is more obvious. Proper reduction fertilization will notreduce the yield ofrice，but also can reduce the nutrient residue in rice fields.