In recent years，in order to achieve the scientific prevention and control of non-point source pollution，a variety of non-point source pollution prevention and control technologies have been developed. However，the application effect of non-point source pollution prevention and control technology varies greatly due to different climate，soil and other conditions. Therefore，the environmental effects，production effects，technical operability and replicability of organic fertilizer instead of chemical fertilizer，drip irrigation reduction fertilization and comprehensive optimization fertilization technology were evaluated and the control effect of different non-point source pollution control technologies was comprehensively evaluated by hierarchical-grey correlation method in this paper. The results showed that compared with traditional fertilization，different non-point source pollution prevention and control technologies could reduce nitrogen loss and improve nitrogen use efficiency in varying degrees，while maintaining or increasing maize yield. The nitrate nitrogen leaching reduced by 43.20%，the nitrogen use efficiency increased by 149.79% and the average individual evaluation value was 0.7500 under the comprehensive optimization fertilization technology. The input of necessary means of production were increased under organic fertilizer instead of chemical fertilizer and drip irrigation reduction fertilization，while the production cost of the comprehensive optimized fertilization technology was averagely reduced by 21.78%. Meanwhile，the average yield of maize increased by 20.54% and the single evaluation value was 0.7290. The operation of comprehensive optimized fertilization technology was simple，so 93.3%-97.3% of farmers were willing to adopt this technology，and 95.5%-97.5% of farmers were familiar with this technology. At the same time，the matching degree of this technology with local policies was in the middle，the score was 85-88，and the single score was 0.9688. The comprehensive evaluation value of the comprehensive optimization fertilization technology calculated by the hierarchical-grey correlation method was the highest，with an average of 0.7649，which was suitable for popularization and application in the prevention and control of non-point source pollution in Hetao irrigation area. The results can provide data support for the realization of green and sustainable development of regional agriculture.