Taking the soil of continuous cultivation of chili peppers for 3 years as the research object，the changes in pH，electrical conductivity，organic matter，organic carbon，total carbon，nutrient content，and enzyme activity of the soil were measured by increasing a mixture of organic fertilizer and composite fertilizer to study the chemical properties of continuous cultivation chili peppers. The results showed that after applying 1.5×104 kg/hm² of organic compost and 7.5×102 kg/hm² of composite fertilizer to chili pepper continuous cropping soil，the soil pH increased by 0.89，and the soil organic matter increased by 5.25 g/kg，compared to the control soil(P<0.05). The content of nutrient elements nitrogen，phosphorus，potassium，calcium，magnesium，and silicon significantly increased(P<0.05)，and the activities of urease，protease，acid phosphatase，and catalase were significantly increased(P<0.05). In conclusion，there was a positive correlation between the improvement effect of soil chemical traits and the amount of organic compost，increasing the application of organic compost improved soil chemical properties，enhanced soil fertility，and increased soil enzyme activity，which could effectively improve the continuous cropping soil of chili peppers.