In order to explore the efficient utilization measures of industrial by-product ammonium sulfate，the effects of three kinds of synergistic ammonium sulfate fertilizers(ASN，nitrification inhibitor + ammonium sulfate； ASG，lipid coating + ammonium sulfate； ASH，humic acid + ammonium sulfate)on the soil nitrogen characteristics，maize growth and development，nitrogen use efficiency were studied，with urea(U)and ammonium sulfate(AS) as the controls. The results showed that，compared with U，AS treatments increased maize yield by 22.63% and nitrogen absorption and utilization rate by 30.92%. Three kinds of enhanced ammonium sulfate fertilizers enhanced the fertilizer efficiency and further promoted maize growth. Maize yield increased by 11.07%，25.26% and 58.92% under ASN，ASG and ASH treatments，respectively，and the nitrogen absorption and utilization rate increased by 6.17，18.27 and 27.57 percentage points，respectively. Nitrogen fertilizer agronomic efficiency increased by 5.10，9.57 and 20.16 kg/kg，respectively. Compared with urea fertilizer，ammonium sulfate fertilizer promoted maize growth and yield and improved the utilization rate of nitrogen fertilizer. Three kinds of enhanced ammonium sulfate fertilizers could further improve maize production and fertilizer efficiency of ammonium sulfate. Among them，humic acid + ammonium sulfate showed perfect effects，which provided a theoretical reference for the application of industrial by-product ammonium sulfate in agriculture.