The contents of toxic and harmful substances such as total nickel，total cobalt and total antimony heavy metal elements in fertilizers were determined by inductively coupled plasma emission spectrometer.This method was accurate and reliable，with good linearity of the calibration curve and low detection limit.The results of all elements in the accuracy test were within the given value range of nickel，cobalt，selenium，vanadium，antimony and thallium standard substance in fertilizer，and the measured element was not affected by coexisting ions in the fertilizer.The recovery rate of the added standard was 102.3%-103.5%，and the relative standard deviation of the precision test was 0%-6.20%，which met the standard requirements.