The effects of iron，manganese and copper fertilizers on crop yield are affected by the differences of growing regions and soil types，fertilization methods and application rates，as well as many other factors.Conducting meta-analysis of above microfertilizers on the grain increase will provide a theoretical basis for the rational application of these fertilizers in grain crops.The research data were collected from China National Knowledge Infrastructure，China Science and Technology Journal Database，Wanfang Data Knowledge Service Platform and Web of Science.The effects of iron，manganese and copper fertilizers on the grain yield of wheat，maize and rice in China were comprehensively analyzed by meta-analysis method，with the response ratio as the effect size and no application of iron，manganese，and copper as the control.The results showed that，the application of iron，manganese and copper fertilizers increased the yield of wheat，corn and rice，with the increase rates of 9.76%，7.09% and 3.68%，respectively.The yield increase effects were different in different years.The effects of soil application of iron fertilizer，manganese fertilizer and copper fertilizer were better than foliar application of them on the grain increase.The application rates with better yield increase effects for iron fertilizer were less than 10 kg/hm²，for manganese fertilizer were more than 30 kg/hm²，and for copper fertilizer were 10-20 kg/hm².Application of iron fertilizer in East China had better yield increase effects(22.68%)than that in other regions，while application of manganese fertilizer and copper fertilizer in West China had better yield increase effects(11.84% and 5.67%)than those in other regions.Soil properties could affect the yield increase effect of iron，manganese and copper fertilizers on crops.Applying iron，manganese and copper fertilizers in the alkaline soil or the soil with organic matter content below 10 g/kg could increase the yield significantly.The application of iron，manganese and copper fertilizers could significantly improve the yield of grain crops，but the reasonable application method and optimal application rates of them，as well as the coordination of them with other fertilizers were necessary to achieve stable and high yield of grain crops.