How to realize nitrogen enrichment and salt repulsion in the crop rhizosphere under drip irrigation conditions to provide a suitable soil environment for the cotton root system is of great significance to improve the yield of salinized cotton in arid areas.Taking typical salinized cotton fields in northern Xinjiang as the object，the effects of different drip application timing of nitrogen fertilizers on the distribution of water，salt and nitrogen in the cotton rhizosphere as well as the growth and yield of cotton were investigated by using the field plot test method under a uniform water and fertilizer management system，i.e.，N 290 kg/hm²，P2O5 110 kg/hm²，K2O 95 kg/hm² and 8 times of fertilizer application with an irrigation quota of 4500 m3/hm²，the partitioning of nitrogen and salinity in the soil profile was studied by regulating the drip time of nitrogen fertilizer.Considering the different duration of each irrigation from seedling to maturity of cotton，generally 6-10 h，the variable t was set as the duration of each irrigation in each fertility period of cotton，and the nitrogen fertilizer input time nodes were used for different treatments as follows:①T1:1 h of dripping before adding nitrogen fertilizer；②T2:(1+1/3t) h of dripping before adding nitrogen fertilizer；③T3:(1+2/3t) h of dripping before adding nitrogen fertilizer.The results showed that different drip application timing of nitrogen fertilizer significantly affected soil salinity content and nitrogen distribution.From the distribution of soil salinity，in the cotton seedling，bud and boll stage，the treatment of first dripping 5-5.6 h and then dripping the nitrogen fertilizer(T3 treatment)significantly reduced the soil rhizosphere salt stress，and the delayed addition of nitrogen fertilizer effectively enhanced the nitrate nitrogen and ammonium nitrogen content in the rhizosphere，which formed a more obvious "fertilizer and salt domain".Nitrogen fertilization at a later stage(T3 treatment)significantly increased the SPAD values of cotton leaves at seedling and bolling stages，which provided suitable conditions for photosynthesis during the critical period of cotton.Cotton boll weight and seed cotton yield increased significantly with the delayed timing of nitrogen fertilizer drip application，and T3 increased boll weight and seed cotton yield by 7.18%，4.04% and 6.35%，1.52%，respectively，compared with T1 and T2 treatments.Comprehensively considering soil salinity，nitrogen distribution，cotton yield and other indicators，it is recommended to adopt nitrogen fertilizer drip timing of (1+2/3t) h，that is，at the seedling，bud and spitting period，it is recommended to drip 5 h before adding nitrogen fertilizer，and at bolling period it is recommended to drip for 5.6 h before adding nitrogen fertilizer.Compared with the customary application of fertilizer by the farmers，the time of dripping of the nitrogen fertilizer is delayed by 3-3.3 h.