In order to investigate the effect of“Jindun”soil conditioner product on the field application of cadmium(Cd)in agricultural land under different climatic and soil production conditions in the Yangtze River Basin，a 2-year 4 planting seasons continuous rice-wheat crop rotation trial was conducted in Xinyi and Changshu cities of Jiangsu Province to study the effects of soil conditioner application on crop seed cadmium content，soil effective Cd content，yield and soil pH. The results showed that:(1)Compared with the control trial，the application of conditioner reduced the Cd content in brown rice by 48.13%-69.57% per season and that in wheat grain by 26.92%-37.04% per season in both locations，and the differences in six planting seasons reached significant levels. (2)Compared with the control trial，the application of soil conditioner increased rice yield by -4.07%-22.00% and wheat yield by -0.84%-30.45% in both locations without reducing the original yield of the crop. (3)Compared with the initial value before the test，soil available Cd was decreased by 0.116-0.148 mg·kg-1(drop by 31.22%-81.12%)and soil pH was increased by 0.87-1.30 units after 2 years of continuous testing. Soil pH of the control trial was reduced by 0.28-0.80 units，the soil conditioner significantly improved soil acidification. (4)Correlation analysis showed that the crop seed Cd content was significantly positively correlated with the available Cd content of the soil，and significantly negatively correlated with soil pH. In conclusion，the“Jindun”soil conditioner products for testing were effective on controlling the risk of Cd pollution on agricultural land in the rice-wheat rotation area，which could help to ensure the safety of agricultural products.