As a typical intensive agricultural area in northern China，improper use of straw and excessive consumption of groundwater are the key factors limiting the sustainable development of agriculture in this region. In particular，it is necessary to clarify the interaction between water-saving irrigation and straw incorporation on crop yield formation，water and nitrogen use efficiency，and to develop an appropriate irrigation method. The field experiment was conducted in 2020-2022，with two straw practices as the main plots:straw incorporation(S1)and straw removal(S0)，and four irrigation methods as sub-plots:surface drip irrigation(DI)，subsurface drip irrigation(SDI)，partial rootzone irrigation under subsurface drip irrigation (PRI)and flood irrigation(FP). The results showed that both straw practices and irrigation methods significantly affected aboveground biomass，nitrogen accumulation，yield，water andnitrogen use efficiency. As compared to S0，the number of wheat spikes increased by 0.66%-25.55% under S1. And the the highest yield and nitrogen accumulation were found in SDI treatment，which were 8346.3 and 167.6 kg/hm²(2020-2021)，8759.3 and 168.5 kg/hm²(2021-2022)，respectively. Straw incorporation had the potential to improve water and nitrogen use efficiency，in which，the average water use efficiency，irrigation water use efficiency，nitrogen use efficiency and partial productivity of nitrogen fertilizer were significantly increased by 57.35%，97.35%，48.75% and 8.75%，respectively，when compared to FP under S1. The two-year average partial productivity of nitrogen fertilizer of the DI，SDI and PRI treatments were increased by 4.8%，8.8% and 0.6%，respectively，when compared to FP treatment. Correlation analysis showed that increasing irrigation increased soil water content under different straw conditions，but significantly reduced wheat water and nitrogen use efficiency. In conclusion，both irrigation and straw practices affected wheat yield，water and nitrogen use efficiency，in which，straw incorporation was beneficial to increase wheat yield，water and nitrogen use efficiency and soil water and inorganic nitrogen content. Subsurface drip irrigation combined with straw incorporation was recommended to achieve the synergistic improvement of yield and water and nitrogen use efficiency.