In order to promote the fertilizer utilization of biogas slurry and residue，this study compounded straw slurry with trace element fertilizers and fertilizer synergist and applied them to leafy vegetables(Chinese cabbage)and eggplant and fruit vegetables(chili pepper)to explore the effects and ecological risks of continuous agricultural use of straw slurry，providing reference for the fertilizer application of straw slurry. The results showed that:(1)Straw slurry had a significant effect on increasing vegetable yield and quality，with comprehensive scores of 2.28，3.51 and 4.53 points increased for chili peppers and two season Chinese cabbage，respectively. The application of trace elements in straw slurry was the most suitable combination method.(2)The application of straw slurry in three consecutive seasons significantly improved the physicochemical properties of the soil in the vegetable field. The application of straw digestate reduced the soil bulk weight by 13.30%，and at the same time increased the soil pH by 1.14，increased water content，porosity，EC value and organic matter content by 30.74%，26.65%，27.97% and 20.21%，respectively.(3)The enrichment ability of cabbage to heavy metals was better than that of pepper，and the application of straw slurry in the three seasons significantly increased the heavy metal contents of vegetables and soil but none of them exceeded the relevant national standards，and in the third season，the contents of As，Cd，Cr，Cu，Hg and Pb in cabbage and soil were increased by 19.4%，17.53%，11.74%，8.12%，13.91%，25.86% compared with the control，respectively，and 7.69%，9.29%，11.50%，10.30%，20.11% and 23.56%，respectively，indicating the risk of heavy metal contamination under long-term application conditions.(4)It was predicted that the continuous application of straw slurry for 15 and 19 years might reach the screening value for soil pollution risk in agricultural land in China(GB 15618—2018)and the soil salt damage standard(EC>1.5 mS/cm)，respectively. In summary，the application of straw slurry in farmland had the effect of improving vegetable yield and quality，and improving soil physicochemical properties. However，long-term application could increase the risk of increasing heavy metal content and soil salt damage in the soil vegetable system.