In order to provide strain resources for the development of bio-fertilizers in saline-alkali land，seven strains of phosphate-solubilizing bacteria were isolated from saline-alkali soil in Xinjiang by phosphate-solubilizing ring method. A salt-tolerant and efficient phosphate-solubilizing bacteria PS4-1 was obtained by liquid phosphate-solubilizing test. It was identified as Enterobacter hormaechei by 16S rRNA gene sequence and phylogenetic tree analysis. The fermentation conditions and phosphate solubilizing ability of strain PS4-1 were analyzed by single factor and orthogonal experiments. The results showed that the strain PS4-1 could grow well under the conditions of temperature 40℃，pH 9.0 and salt concentration 5%. The optimum fermentation conditions were temperature 30℃，pH 7.0 and salt concentration 0.5%. The utilization of carbon sources by strain PS4-1 was maltose > glucose > sucrose > starch > sodium citrate，and the utilization of nitrogen sources was ammonium chloride > peptone > ammonium sulfate > urea. The optimal phosphate solubilization conditions were as follows :maltose 35 g/L，ammonium chloride 0.05 g/L，initial pH 6.0，salt concentration 0.5%，inoculation amount 3%，temperature 35℃. Under these conditions，the dissolution amount of tricalcium phosphate by strain PS4-1 could reach 480.23 mg/L，which was 41.79% higher than that before optimization. In summary，Enterobacter hormaechei PS4-1 had certain temperature resistance，saline-alkali resistance and good phosphorus solubility，which could provide strain resources for the management of phosphorus pool in saline-alkali land.