In order to compare the effects of different synergistic urea application on apple growth, and to screen suitable synergistic nitrogen fertilizer application methods for apples, this paper investigated the effects of different synergistic urea application on apple growth, yield, quality and soil nitrogen supply capacity. The experiment was set up with five treatments: no nitrogen fertilizer (CK), farmers routinely applying ordinary urea (U), 3:7 wrap-around controlled-release doped urea (CU1), 3:7 wrap-around controlled-release doped urea 50% + follow-up application of ordinary urea 50% (CU2), and 3:7 humic acid doped urea 50% + follow-up application of humic acid urea 50% (FZU). The field experiment was laid out in Qixia City, Shandong Province, and the test variety was 10-year-old apple red Fuji. The effects of different fertilization treatments on apple growth, yield and quality, nitrogen utilization and soil nitrogen supply capacity were analyzed. The results showed that different synergistic urea treatments could significantly promote the growth of apple in spring and autumn, improve leaf SPAD value, apple yield and quality, in which the FZU treatment significantly increased the yield by 9.07% compared with the U treatment, and the fruit VC content, soluble solids, solid-acid ratio, and fruit shape index were significantly increased by 3.79%, 11.80%, 23.55%, and 4.60%, and the CU2 treatment significantly increased the yield and quality of apple in spring and autumn. The effect of CU2 treatment was most obvious on the improvement of spring and autumn growth.CU2 treatment significantly increased the nitrogen accumulation of new shoots and fruit nitrogen accumulation, nitrogen fertilizer agronomic efficiency, nitrogen fertilizer bias productivity and nitrogen utilization of apple in all the reproductive periods, and the above indexes were significantly increased by 5.94%~81.54%, 42.79%, 12.81%, 62.89%, 12.79% compared with that of the U treatment, respectively. The FZU treatment had the best effect in increasing soil NO3-^{-N and NH}4⁺-N content. the FZU treatment significantly increased the NH4⁺-N content of soil at different depths of the profile, decreased the NO3^--N content of soil at 60~80 cm depth, and reduced the risk of leaching of NO3^--N. The treatment of 3:7 humic acid mixed with urea with 50% N application at budding stage + humic acid urea with 50% N chase at expansion stage can be used as the optimal N application pattern for apples in Shandong.